Oestrogen-free contraceptive pill(12)
Order Cerazette when it’s convenient for you. Our online service allows you to complete a short assessment online and have your online doctor check it for you. If they agree Cerazette is right for you, your order will be sent to your door or to your preferred post office to pick up.
If you need emergency contraception, you can also order the morning after pill here.
The active ingredient in Cerazette is desogestrel.
Who can take Cerazette?
Most women who want to prevent pregnancy can take Cerazette. You can’t take Cerazette if you’re pregnant. However, you can take Cerazette if you’re breastfeeding, unlike the combined contraceptives that contain oestrogen – these can’t be given to mothers breastfeeding very young babies.
In addition, women who smoke can take Cerazette as it is oestrogen-free. Oestrogen in combination with smoking significantly increases cardiovascular risks and the risk of venous thromboembolism (VTE), i.e. blood clots and deep vein thrombosis, particularly in women over 35.
Cerazette side effects
As Cerazette does not contain oestrogen, users are not at risk of some of the side effects associated with taking a combined contraceptive.
However, many women may experience bleeding irregularities whilst on Cerazette and common side effects can include acne, loss of libido, nausea, headaches, and breast pain.
Cerazette is an oestrogen-free contraceptive pill containing synthetic progesterone (desogestrel). It’s often known as a progesterone only pill (POP), or mini pill. It is taken to prevent pregnancy. It is an option for women who want to or need to avoid oestrogen. Cerazette must be taken within a 12-hour window around a fixed time each day to prevent pregnancy. Some other oestrogen-free pills have to be taken within a more restrictive 3-hour window, so this is one of the attractions of taking Cerazette.
How does Cerazette work? – the active ingredient in Cerazette, desogestrel, prevents ovulation (egg release from the ovaries) and increases the thickness of the womb’s mucus lining, which makes it more difficult for sperm to access the womb from the vagina.
If you want or need a POP instead of a combined oral contraceptive (COC), Cerazette may theoretically be more effective than traditional POPs. Cerazette, with its 12 hour window, provides more flexibility than many other POPs which only have a 3 hour window. Cerazette also acts differently from other POPs: it stops ovulation in 97% of cycles, whereas most POPs don’t consistently suppress ovulation, but depend on cervical mucus for the most part of their effects.
Progesterone only pills overall are more than 99% effective meaning that less than 1 per 100 women per year become pregnant when using this perfectly.
POPs allow you to use contraception during breastfeeding, and are the recommended type of contraceptive for smokers over 35 years old and for women with body mass index (BMI) more than 35 kg/m2.
What other advantages does Cerazette have? – since Cerazette doesn’t contain oestrogen, it doesn’t have the risk of deep vein thrombosis associated with combined oral contraceptives (COCs). Cerazette can often be taken by women who’ve been advised not to take a combined pill – for example, women with high blood pressure, migraines with aura, and certain heart conditions.
What are the disadvantages of Cerazette? – one disadvantage is that your bleeding pattern is likely to change with Cerazette (but some women might see this as an advantage). In the first 3 months of starting Cerazette, frequent bleeding, prolonged bleeding, and infrequent bleeding are all more common that with traditional POPs. When taking Cerazette for more than 1 year:
- 5 out of 10 women can expect to have infrequent or no periods (always check a pregnancy test if you haven’t taken the pill correctly)
- 4 out of 10 women can expect to have regular spotting/bleeding episodes (3 to 5 episodes in 3 months)
- 1 out of 10 women can expect to have frequent bleeding (more than 6 episodes in 3 months)
- 2 out of 10 will experience prolonged bleeding (episodes lasting more than 14 days)
If after 3 months bleeding is persistently prolonged or frequent, you have been on Cerazette longer than this and notice a change in your bleeding pattern or you notice bleeding after sex, pain during sex or a change in your vaginal discharge please see your GP to make sure there are no other underlying causes for your bleeding.
In addition, as with all oral contraceptives, you need to take the pill at roughly the same time every day. As day to day life can make remembering to take the pill on time difficult, the effectiveness of POPs decreases to 91% when they’re not taken perfectly.
Cerazette has some potential side effects including headaches, acne, nausea, loss of libido, and breast pain.
Do I still need to use a condom if I am taking Cerazette? – taking Cerazette does not protect you from STIs (sexually transmitted infections). Using a condom is the best way to provide STI protection, and it is a good back up precaution for preventing pregnancy.
Can I drink alcohol whilst taking Cerazette? – alcohol does not interact with Cerazette and will not make the contraceptive treatment any less effective. Therefore, it is medically acceptable to drink whilst on Cerazette. However, drinking too much alcohol can have very severe impacts on your general health and so should be avoided.
How does Cerazette compare to other contraceptives? – many of the other oral contraceptives are combined, meaning they contain more than one synthetic hormone (usually various versions of oestrogen and progesterone). However, Cerazette contains only synthetic progesterone (desogestrel) so it is one of the “progesterone only” pills or “POPs”. Cerazette must be taken every day without a break between packs, regardless of cycle, unlike the combined contraceptives, which are traditionally taken for 21 days per cycle, starting on the first day of your period. Both combined contraceptives and POPs are more than 99% effective at preventing pregnancy when taken correctly. Cerazette is more effective than condoms and the female diaphragm. But when Cerazette isn’t used perfectly, it’s less effective than long-acting reversible contraception like the progesterone only injection, progesterone only implant, levonorgestrel intrauterine system, and copper intrauterine device.
Cerazette is different from the other progesterone only pills as it actually stops ovulation, theoretically making it more effective. The other POPs don’t do this, with the exception of Cerelle.
Are there any other progesterone-only pills? – yes, there are a wide range of POPs including Cerelle, Micronor, Norgeston and Noriday. However, Cerazette and Cerelle are probably the best of the progesterone only pills, because they can be taken within a 12-hour time frame around a fixed time each day, compared to a 3-hour window with other POPs. This factor can help you stick to a more effective pill-taking routine. Cerazette and Cerelle also stop ovulation, unlike the other POPs, making them theoretically more effective.
When do I start treatment? – since you need to take Cerazette every day for the treatment to be effective, it does not matter exactly when you start taking the Cerazette. If you have regular periods and start Cerazette within days 1 to 5 of your period, it’s effective immediately. Otherwise it will take 48 hours for the treatment to be effective, so during this time you need to take extra precautions and wear a condom. Talk to your doctor about the best time to start Cerazette if you’ve given birth recently, had a termination of pregnancy or a miscarriage, don’t have regular periods, or have taken emergency contraception.
What dosage do I take? – a Cerazette tablet contains 75 micrograms of Desogestrel. You should take one per day. Taking more than this will not have an adverse health effect, but it will not improve your protection and may make you feel nauseous.
You should take the pill at the same time every day, so that you are taking a pill roughly every 24 hours. If you don’t take a pill in your assigned 12-hour window (e.g. it’s more than 36 hours since you last took a Cerazette pill), you should take the missed pill straight away and take your next pill at the usual time, even if this means taking 2 pills in one day. You should also use condoms if you have sex within 48 hours or taking the next pill. If you have unprotected sex within the 48 hour timeframe, you’re at risk of pregnancy and may need emergency contraception.
How will I know if Cerazette is working? – there is no sure way of telling if your treatment is working unless you can test whether you are pregnant or not. Be assured that if you take your contraceptive pill correctly, you will be 99% protected from getting pregnant. It is normal that periods are suppressed or become infrequent or light whilst using Ceramzette. You are not necessarily pregnant if you miss a period whilst on Cerazette. However, if you are concerned, take a pregnancy test or talk to your doctor.
What if I am sick? – if you vomit or have diarrhoea within 2 hours of taking the pill, it may not have been absorbed into your body properly. In this case, take another pill as soon as possible within the 12-hour window and then continue treatment as usual.
Can I still get pregnant if I stop taking Cerazette? – yes, the contraceptive is reversible. Once you stop the mini pill, there’s a normal chance you will get pregnant. However, if you take your pills consistently and as recommended, protection against pregnancy is 99% effective.
As Cerazette does not contain oestrogen, users are not at risk to some of the side effects associated with taking a combined contraceptive.
Many women will have a change in bleeding pattern with Cerazette.
Common side effects include:
- Loss of libido
- Breast pain
These will affect around 10% of women.
Uncommon side effects include:
- Vaginal infections
- Contact lens intolerance
- Alopecia, ovarian cysts
- Pain during menstruation (Cerazette can also be used to treat this)
These will be experienced by between 1 and 10% of women.
Rare side effects include:
- urticaria (a disease affecting the skin through changes to the immune system)
- erythema nodosum (inflammation of fat cells under the skin, causing redness)
- in very rare cases, the breasts may give off discharge or an ectopic pregnancy may be experienced. However, Cerazette reduces the risk of ectopic pregnancy overall by reducing the risk of pregnancy. If you experience nipple discharge, see your GP, and if you have a positive pregnancy test with any abdominal pain, dizziness, bleeding, diarrhoea, vomiting, or changes to your urine, seek medical assistance immediately
- a link between POPs and breast cancer has not been proven but cannot be completely excluded due to limited studies
- although listed as potential side effects it is not proven that Cerazette causes weight gain or mood disturbance
You must not take Cerazette if:
- you have a severe allergy to anything in Cerazette
- you have a lactose intolerance
- you have severe liver disease/a history of liver disease from which you have never fully recovered, including liver cancer
- you suffer from, or have suffered from, sex-steroid sensitive malignancies including breast cancer
- you have unexplained vaginal bleeding
- you’re pregnant
- you’re taking cerazette and have a stroke or ischaemic heart disease
You must discuss with your doctor if you:
- are under 16
- are over 50
- have a venous thromboembolism (deep vein thrombosis or pulmonary embolus)
- have diabetes
- have uncontrolled high blood pressure
- have chloasma (brown patching on your skin)
- suffer from depression
- are taking any regular medications or have finished any medications in the last 28 days, including over the counter treatments and herbal remedies, as some may affect the ability of Cerazette to prevent pregnancy or the absorption of the pill
Also, if any of these effects start when you begin to take Cerazette, you should stop the treatment, use barrier protection, and speak to your doctor as soon as possible.
Please read the patient information leaflet or speak with your doctor for a full list of medications/ treatments which may interact with Cerazette.
Risk of pregnancy – once you stop taking your pill, the hormones in your body will subside within a few days. Therefore, you will need to use contraception immediately after you stop taking the pill to prevent pregnancy. If you’re sexually active, you could become pregnant after 24 hours of taking your last pill.
Periods going back to normal – you’re likely to have a period within a few weeks of stopping Cerazette and should see your doctor if you don’t. You can also expect your periods to be as they were before you started taking Cerazette. If you would like to come off Cerazette, you can get advice from your GP, nurse or pharmacist. If you don’t want to get pregnant, you should use other forms of contraception such as condoms.
Contraceptive pills are a reliable way of reducing your risk of getting pregnant from sex. Zava offers most common brands of pill, so you can order your preferred brand by visiting our contraceptive pill service page.
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