Xenical is a prescription-only weight loss medication that can help you lose more than 10% of your weight in 3-6 months
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Xenical is a weight loss medication for treating obese patients, combined with healthy eating and exercise. Xenical weight loss pills come in pills of 120mg, which you take 3 times a day. It is only available on prescription.
If you have any questions about Xenical, weight loss treatment, or your health, you can message our doctors for free advice through your account. You can do this before you request treatment or later once you begin treatment.
1 month / 84 capsule(s) - £59.95
Xenical is a prescription pill for weight loss. It is a branded version of Orlistat, and is available in a dosage of 120mg. Xenical works by stopping your body from absorbing some of the fat from your meals, which is instead passed on as waste when you go to the bathroom.
Xenical is an effective weight loss pill, and alongside dieting and exercise it can help you lose more than 10% of your body weight in 3-6 months.
What is another name for Xenical?
Xenical is a branded version of Orlistat, and is available on prescription at a dosage of 120mg. Alli is another branded version of Orlistat that is only available at a dose of 60mg, but you can get it without a prescription.
Xenical is a weight loss medication for people who are obese (BMI of 30 or over). It is usually only prescribed to those who have tried to lose weight in the past, but haven’t been able to. It is used alongside dieting and exercise to promote healthy weight loss.
Xenical weight loss pills work by changing the way your body digests and absorbs fat. It can block up to 30% of the dietary fat that is usually absorbed from the food you eat. This helps you lose weight, as the fat is passed on when you go to the bathroom instead of being absorbed into your body.
What does Xenical do to your body?
Xenical tablets belong to a group of medications called “lipase inhibitors”. These medications block an enzyme for digesting fat in your intestines called lipase. This prevents your body from absorbing some of the fat in your food. Instead, the fat is passed out of your body as stool waste.
How long does Xenical take to work?
Xenical can start working as early as 2 days from the start of treatment, but it may take up to 2 weeks for you to start seeing results. You should expect optimal weight loss results within the first 3 months of taking Xenical.
Speak to your doctor if you have not lost at least 5% of your body weight (your weight at the start of treatment), after taking Xenical for 3 months.
Xenical (Orlistat) has been proven through clinical trials to be one of the most safest and effective medicines for treating obesity. It prevents your body from absorbing up to 30% of the dietary fat from your meals, and can help you lose more than 10% of your body weight within 6 months of treatment.
How much weight can you lose on Xenical in a month?
You can expect to lose 2kg-4kg in the first month when you start taking Xenical tablets. These results can vary from person to person, based on factors like starting weight, underlying medical conditions, and how well you keep up with other complementary lifestyle changes such as dieting and exercise.
How long does it take to see results from Xenical?
Xenical starts to work within 1-2 days after first taking it, but you may not see results straight away. Some patients notice visible weight loss after 2 weeks of taking Xenical, though it may take a little longer depending on your body and lifestyle changes. Most patients say they see the best results in the first 3 months of taking Xenical.
Swallow 1 tablet of Xenical after every main meal that contains fat, up to 3 times per day. This is usually at breakfast, lunch, and dinner. You should swallow your capsules whole with water. If you eat a meal that doesn’t contain fat, you don’t need to take Xenical.
Who can use Xenical?
Xenical is recommended for people:
- with a BMI of over 30kg/m2
- with a BMI of over 28kg/m2, and other medical conditions like type 2 diabetes or high blood pressure
- who have tried other weight loss options but have been unsuccessful
Our doctors will take your BMI and all of your medical history into consideration and may prescribe off-label when making a decision about treatment.
When should I take Xenical?
You should take Xenical tablets with every main meal that contains fat, up to 3 times per day.
You can take Xenical immediately before, during or up to 1 hour after a main meal, containing fat. Do not take Xenical if you miss a meal or the meal doesn’t contain fat.
What is the best way to use Xenical?
The best way to use Xenical is alongside complementary lifestyle changes that can help you lose weight. Working with your doctor or another weight loss specialist to create a calorie-controlled diet plan and exercise routine will make Xenical even more effective in helping you lose weight.
How long can you take Xenical for?
You typically take Xenical for 3-6 months, but it can be prescribed for up to a year in some cases. It is thought that there is no time limit on how long you can safely take Xenical for, as long as you are seeing positive results from it. However, you should not continue to take Xenical longer without an assessment with your doctor.
Can you skip a day on Xenical?
You only need to take Xenical after eating a meal that contains fat, so if you go for a day without eating a fatty meal then you could skip a day of Xenical.
If you accidentally skip or miss your Xenical dose, take it as soon as you remember as long as it is within an hour of your last meal, then continue your next dose as usual. If it is outside this time or you miss several doses, speak to your doctor as soon as possible for advice on what to do next.
There is no such thing as a “normal” BMI, though there is a range that is defined as “healthy.” A healthy BMI is between 18.5 and 24.9. You are classed as overweight if your BMI is between 25 and 29.9, and obese if your BMI is above 30.
Xenical is usually only prescribed to those who are obese, or who have a BMI of 30+. In some cases Xenical may be prescribed to those who have a BMI of 28, such as if they have high blood pressure or type 2 diabetes.
Xenical is only available at a dosage of 120mg. This dosage is taken 3 times a day with each meal, for a total dosage of 360mg of Xenical per day.
Xenical is a branded version of Orlistat, which is also available at a dose of 60mg under the brand name Alli. This medication is exactly the same as Xenical, but is slightly less effective for weight loss because it’s a lower dosage.
Cost Price per Pill 84 capsules (4 week supply)
Xenical is a prescription-only medication, so it can only be bought with a prescription in the UK. You can request Xenical online from legitimate UK registered providers who are regulated by the CQC and MHRA, like ZAVA.
Avoid buying Xenical from online services that offer Xenical without prescription. These websites could be selling fake medicines which are potentially unsafe and are a waste of money too.
How to buy Xenical online?
You can buy Xenical online safely and legally from trusted websites such as ZAVA Online Doctor. In order to buy Xenical online, you’ll first have to complete a short online questionnaire about your health. This helps our doctors make sure Xenical is safe and appropriate for you.
Can you buy Xenical over the counter?
No, Xenical is a prescription-only medication, so you cannot get it over the counter without a doctor’s prescription.
Alli is a weight loss medication that uses the same active ingredient as Xenical, but at a lower dosage. Alli contains 60mg of Orlistat, and is available over the counter at most pharmacies in the UK.
The main benefits of Xenical include:
- lower weight
- lower BMI
- lower cholesterol levels
Xenical may also be beneficial for those with high blood pressure, and can help people with diabetes to control their blood sugar levels.
Like with all medicines, there is a risk of developing side effects when taking Xenical, although not everyone will experience them.
Some common Xenical side effects are:
- stomach discomfort
- urgency to empty your bowels
- oily or fatty stools
- low blood glucose (in people with diabetes)
- passing wind often
Some less common Xenical side effects are:
- pain in the anal area
- soft stools or diarrhoea
If you experience any side effects (including those not listed above) or allergic reactions when taking Xenical, consult your doctor immediately. Some common allergic reaction signs are:
- difficulty breathing
- itching and skin rash
- wheals (patches on the skin)
- nausea and vomiting
- feeling unwell
Seek immediate medical attention if you experience any of these allergic reactions after taking Xenical.
Who should not take Xenical?
Do not take Xenical if you:
- are allergic to any of its ingredients
- have cholestasis (a liver condition)
- have chronic malabsorptive disorder
- are breastfeeding
If you have any of the following conditions, inform your doctor before taking Xenical as you may need to make certain adjustments:
- taking medicines for diabetes
- taking medicines for high cholesterol
- chronic kidney disease
- if you are using the contraceptive pill
- if you have a high daily fat intake
Drug interactions with Xenical
You should always inform your doctor of all medicines you are currently taking or have taken recently, including over the counter drugs and herbal supplements.
The following medicines may interact with Xenical tablets:
- anticoagulants (Warfarin)
- thyroid medicines
- medicines to treat HIV
- medicines for depression or anxiety
- antiepileptic medicines
- antidiabetic medicines (Acarbose)
For a full list of Xenical side effects, cautions and drug interactions, read the patient information leaflet supplied with your medicine.
Can I take Xenical if I am pregnant or breastfeeding?
No, you must not take Xenical if you are pregnant or breastfeeding. This is because the medicine could harm your (unborn) child. Inform your doctor before taking Xenical if you are planning to become pregnant.
Xenical is an effective weight loss treatment for a lot of people, but it may not be right for you. Fortunately, there are alternative weight loss medications available to help you.
Orlistat vs Xenical
Xenical tablets are a branded version of Orlistat, which means that they are the same medication and work in the exact same way. The only difference between Xenical and Orlistat is the name on the box, and the price.
Xenical vs Alli
Xenical and Alli are branded versions of Orlistat, which means they both work in the same way. However, Alli is only available at the lower dosage of 60mg, while Xenical is available at 120mg. Because it is a higher dosage, Xenical is more effective for most people than Alli.
Unlike Xenical, Alli is available over the counter, while Xenical requires a prescription before you can get it.
Wegovy is a weight loss injection that works differently to Xenical tablets. While Xenical helps you lose weight by changing how your body absorbs fat, Wegovy works by reducing your appetite. This helps you lose weight by reducing your calorie intake, as you don’t need to eat as much to feel full.
Wegovy might be a good alternative if you do not like swallowing tablets, or if Xenical is not safe for you to take.
Active Ingredient(s) Price Orlistat (Pill)
Naltrexone and Bupropion
Yes, Xenical is a good option for weight loss, especially when used alongside complementary lifestyle changes like dieting and exercise. Xenical is highly effective for weight loss and can help you lose more than 10% of your body weight in just 3-6 months. Xenical is also a safe option for many people to take, with no widely reported serious side effects.
Frequently asked questions
How do I know if Xenical is working?
Xenical starts working in 1-2 days, but you might not see results for up to 2 weeks. One of the more obvious signs that Xenical is working is oilier poops than normal, which show that unabsorbed fat is being passed on through your stool.
Does Xenical work on existing fat?
No, Xenical will not reduce or burn existing fat, it reduces the amount of fat your body absorbs from future meals.
Can I take Xenical if I am pregnant or breastfeeding?
No, it is currently not recommended to take Xenical when pregnant or breastfeeding. This is because the medication may pass on to your newborn child through breast milk, or to your unborn baby in the womb.
Does Xenical make you poop?
Yes, Xenical can make you need to poop more urgently or more frequently if you eat a fatty meal. This is because some of the fat you eat will be passed on when you go to the bathroom, so if you eat a very fatty meal, it increases the amount of fat in your poop.
Dr Crystal Wyllie Accreditations: MBBS, MRCGP (2015), DFSRH, DRCOG (2018)
Crystal qualified in Medicine at Barts and the London School of Medicine and Dentistry in 2010. She then trained as a GP in London hospitals and practices. She has a particular interest in reproductive, sexual and women’s health.Meet our doctors
Last reviewed: 28 Nov 2023
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Information for patients taking orlistat (Xenical), NHS [accessed October 2023]
Orlistat, Statpearls [accessed October 2023]
Weight Loss Treatment, NHS [accessed October 2023]