Cialis
Cialis is a prescription-only erectile dysfunction medication that contains the active ingredient tadalafil.
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Erectile dysfunction pills that work as well as Cialis
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Cialis is the longest-lasting medication for erectile dysfunction. It starts working in just 30 minutes, and the effects can last up to 36 hours. Cialis is a branded treatment that contains the active ingredient tadalafil. This is a PDE-5 inhibitor, so it works to increase blood flow to your penis so you can get and keep an erection during sex.
Cialis works for up to 75% of men who try it. There are 2 available doses which are 10mg and 20mg and you’ll usually take the lower dose first. Cialis is manufactured by Eli Lilly and Company Limited and you can find more about the medication in the patient information leaflet.
Prices
4 tablet(s) - £45.99
8 tablet(s) - £81.99
12 tablet(s) - £117.99
16 tablet(s) - £152.99
4 tablet(s) - £45.99
8 tablet(s) - £88.00
12 tablet(s) - £119.99
16 tablet(s) - £149.00
About Cialis
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Cialis is a medication you can take to help you get and keep an erection. It contains the active ingredient tadalafil, which belongs to a group of medicines called phosphodiesterase type-5 (PDE5) inhibitors.
PDE5 inhibitors work by relaxing the blood vessels and increasing blood flow to the penis when you’re aroused, allowing you to sustain an erection. This makes Cialis an effective treatment for erectile dysfunction (ED), when you find it difficult to get a natural erection.
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Cialis works by getting more blood to flow into the penis, so you can get an erection when you’re sexually aroused.
When you are sexually stimulated, your nerves release a chemical which relaxes your blood vessels (makes them wider). This allows blood to rush into your penis and cause an erection. Cialis helps keep this chemical in your blood so you can maintain an erection.
As this chemical is only released during sexual activity, you will only get an erection with Cialis when you feel like having sex.
How quickly does Cialis work?
Cialis starts working within 30 minutes of taking it, so it’s recommended to take Cialis 30 to 60 minutes before you want to have sex.
How long does Cialis last?
The effects of Cialis will remain for around 36 hours, which means you can take fewer tablets throughout the week. This is suitable if you have sex once or twice a week and do not want to take a tablet every time you have sex.
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You should take Cialis as your doctor has directed you to do so. For most people, the starting dose of Cialis is one 10mg tablet before sex, a maximum of one tablet per day.
To take Cialis:
- take 1 Cialis tablet at least 30 minutes before you plan to have sex
- swallow the tablet whole with water
You can take Cialis with or without food but you should avoid grapefruit juice or fresh grapefruits. Grapefruit can change the effectiveness of Cialis by interfering with how your body breaks it down to clear it from your system.
Try to limit your alcohol intake on the days you take Cialis, as it can make it difficult for you to get an erection.
Can I take Cialis every day?
You should not take Cialis tablets every day. Cialis stays in your body for around 36 hours. This means you’ll still benefit from its effects a day and a half after you take the tablet. Therefore, Cialis is often called the ‘weekend pill’.
If you prefer to take a daily tablet that does not interrupt when you have sex, you can request Cialis Daily. Cialis Daily is available as a 2.5mg and 5mg tablet and does not need to be taken before sexual activity. You take 1 Cialis Daily tablet every day without taking a break. It’s recommended if you have sex frequently (more than 2 times a week).
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To get the best effect when taking Cialis, you should take the tablets exactly as directed by your doctor. This means that it’ll work when you need it to, and you are less likely to get unwanted side effects. Other things you can to do make Cialis more effective:
- Make sure you’re sexually stimulated with enough foreplay. Cialis only works when you are aroused, it doesn’t just give you an erection.
- Avoid drinking alcohol when taking Cialis, as alcohol can make it harder to get an erection. This can make Cialis less likely to work and increases the risk of side effects.
- Avoid drinking grapefruit juice, as this can interact with Cialis and cause side effects
- Avoid eating fatty meals before taking Cialis, as it may take longer for Cialis to start working.
If Cialis doesn’t work for you in the expected timeframe, do not take more than your prescribed dosage. Taking too much Cialis can cause serious side effects, and could even result in damage to your penis.
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Cialis tablets come in 10mg and 20mg doses. The dose of your Cialis tablets tells you how much of the medicine is in them. As a rule: the higher the dose, the stronger the medication.
10mg or 20mg Cialis tablets are to be taken as and when you need them. Take your tablet about 30 to 60 minutes before you are going to have sex.
If you’re expecting to have regular sex, your doctor might recommend that you take Cialis daily, which is a different Cialis medication that comes in 2.5mg and 5mg tablets. 5mg doses of Cialis are suitable for taking every day.
Which Cialis dosage should I start with?
The usual starting dose for Cialis is 10mg if you are taking it before you have sex and 5mg if you are taking it as a daily dose. These dosages are effective for most men and are the most popularly prescribed.
If you try these dosages and find that they do not work for you, you can speak to your doctor about taking a higher dose of Cialis. The maximum dose is 20mg. Do not increase your dosage without speaking with a doctor first, as it may not be safe.
What is the difference between Cialis and Cialis Daily?
The main differences between Cialis and Cialis Daily are:
- When you take it: Cialis is an on-demand ED medication, so you take it before you want to have sex. Cialis Daily is taken every day, so you’re always ready.
- Who it’s recommended for: Cialis is recommended for men who have sex once or twice a week and Cialis Daily is recommended for men who have sex more than twice a week.
- Dosage: Cialis comes in 10mg and 20mg doses, while Cialis Daily comes in 2.5mg and 5mg doses.
They both contain tadalafil as the active ingredient and work in the same way.
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Yes, you can buy Cialis online. Cialis is a prescription-only medication, so you will need a prescription from a licensed healthcare professional before you are able to buy it.
You should only request Cialis online from trusted online doctor services like ZAVA. We are monitored and regulated to ensure you receive safe and genuine medication.
Getting Cialis with a prescription from ZAVA is quick and convenient, with no need for a face-to-face appointment.
- Complete a short online medical questionnaire – Share details about your health so our doctors can ensure Cialis is right for you.
- Order and pay online – Sign in or create your ZAVA account, select Cialis, and securely make your payment.
- Doctor review and approval – A UK-licensed doctor will check your health information and approve your prescription request if Cialis is safe and appropriate for you.
- Fast and discreet delivery – If approved, Cialis will be delivered discreetly to your home or a local post office for collection.
Can I buy Cialis over the counter?
No, you cannot get Cialis over the counter as it is a prescription-only medication. However, there is a type of Cialis called Cialis Together, which is available over the counter in 10mg tablets only. If you try Cialis Together and find the dose isn’t working well enough after trying it 8 times, speak to a doctor about getting a prescription for 20mg Cialis tablets instead.
Can I get Cialis on the NHS?
You may be able to get Cialis on the NHS, but this depends on the prescribing guidelines for your area. You will need to speak to your GP and arrange an appointment to find out if you can get Cialis on the NHS.
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You may have a few or no side effects when taking Cialis. Some side effects of Cialis are more common than others. If a side effect is listed below, it does not mean you will definitely get it when you take Cialis.
Some common side effects of Cialis include:
- headache
- muscle aches
- back pain
- facial flushing
- nasal congestion
- indigestion
Uncommon side effects happen less often. These side effects will usually disappear after a few hours.
Uncommon side effects of Cialis include:
- dizziness
- feeling sick or being sick
- reflux
- blood in urine
- prolonged erections
- feeling your heartbeat
- a fast or irregular heartbeat
- changes to your blood pressure
- nosebleeds
- tiredness
If you get any side effects that do not go away after a few hours every time you take Cialis, speak to your doctor. They may suggest changing to an alternative ED medication.
You should stop taking Cialis and contact 999 right away if you have:
- an allergic reaction or a rash
- chest pain
- priapism (a prolonged erection that lasts for more than 4 hours)
- sudden loss of vision
If you get chest pain after taking Cialis, do not take medication that contains nitrates to relieve the pain. This includes glyceryl trinitrate spray or nitrate tablets. For more details on the side effects of Cialis, read the patient information leaflet inside your pack.
How to avoid Cialis side effects
While there’s no way to completely avoid side effects, as Cialis can affect everyone a little differently, there are some things you can do to reduce the risk of side effects:
- Tell your doctor about any medications you are taking and any pre-existing conditions you have. Cialis can interact with certain medications, and may not be suitable for people with conditions such as blood pressure problems.
- Avoid drinking alcohol when taking Cialis. Alcohol can increase your risk of side effects, as well as make the medication less effective at helping you get an erection.
- Take Cialis exactly as prescribed, and do not increase your dosage without talking with your doctor first. If you take more Cialis than prescribed, you could cause unwanted side effects such as damage to your penis.
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You can take Cialis if you are a man over the age of 18 and struggle to get an erection when having sex.
You should not take Cialis if you:
- are a woman
- are under 18 years old
- are allergic to tadalafil or any other ingredients in Cialis
- are taking medicines that contain nitrates, such as nitroglycerin or isosorbide mononitrate
- are taking products that contain amyl nitrite (also called ‘poppers’)
- have a history of blood clots
- have blood pressure problems
- have a personal or family history of visual problems
- are taking riociguat, which is used to treat pulmonary arterial hypertension
Also speak to your doctor before taking Cialis if you have:
- sickle cell anaemia
- multiple myeloma
- heart problems
- leukaemia
- any penis deformation, including Peyronie’s disease
- liver or kidney problems
- lactose intolerance
Your doctor will be able to advise whether Cialis is suitable for you to use.
For further information and guidance please read the Cialis patient information leaflet.
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Every Cialis tablet contains the active ingredient tadalafil. Depending on the dosage, each pill may contain 10 or 20mg of tadalafil, as well as the additional non-active ingredients: lactose monohydrate, magnesium stearate, triacetin, iron oxide yellow (E172), croscarmellose sodium, hydroxypropyl cellulose, microcrystalline cellulose, sodium lauryl sulphate, titanium dioxide (E171), talc and hypromellose.
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Cialis can interact with other medications that you might be taking. Speak to your doctor or pharmacist if you are taking:
- riociguat, used to treat pulmonary arterial hypertension
- alpha-blockers, including doxazosin
- high blood pressure treatment
- 5-alpha reductase inhibitors, used to treat benign prostatic hyperplasia, such as finasteride
- antifungal medication, such as ketoconazole and itraconazole
- protease inhibitors, like ritonavir used in HIV treatment
- epilepsy medication, including carbamazepine, phenytoin or phenobarbital
- antibiotics, including rifampicin, erythromycin and clarithromycin
- other erectile dysfunction treatments, such as alprostadil
If you take any of the above medications, your doctor can suggest the Cialis dose that is most suitable for you or an alternative ED treatment.
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If you want to try a different ED medication to Cialis, your options include:
- Viagra (also known as sildenafil)
- Levitra
- Spedra
These medications work similarly to Cialis as they all belong to the same medication group of PDE5 inhibitors.
Cialis vs Viagra
Cialis and Viagra are the 2 most popular medications for erectile dysfunction, and it can be hard to know which one is best for you. They work in similar ways but have some differences such as how long they take to start working, and how long they last.
Cialis vs Viagra comparison table
Cialis Viagra Time to start working 30 minutes
30-60 minutes
How long it lasts Up to 36 hours
4-6 hours
Available dosages 2.5mg, 5mg (Cialis Daily) 10mg, 20mg (Cialis)
25mg, 50mg, 100mg
Over the counter? Cialis Together
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Cialis is one of the most commonly prescribed medications for erectile dysfunction in the UK and is effective for most men.
Patient reviews for Cialis are positive, and this medication has an average rating of 8.5 out of 10 on drugs.com. 82% of patients reported a positive experience, while only 9% reported a negative experience while using Cialis.
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Frequently asked questions
What is the difference between Cialis and Viagra?
The main difference between Cialis and Viagra lies in the time frame during which they are effective:
- Cialis works for a period of up to 36 hours. This means that if you are sexually stimulated within this period of time, Cialis will help you get an erection. It is often referred to as a “weekend pill”, as it allows you to have spontaneous sex several times during the specified window of time.
- Viagra is effective for up to 4 hours and therefore requires that you plan ahead.
Both Viagra and Cialis take 30 to 60 minutes to work, so you should take the tablet at least half an hour before intercourse.
The dosage for each medication is also different, as the active ingredient is different. Viagra comes in 25mg, 50mg, and 100mg tablets, whilst Cialis comes in 10mg or 20mg tablets. You can also get Cialis Daily, which is a 2.5mg or 5mg tablet you take once a day.
Is Cialis better than Viagra?
Both Cialis and Viagra are just as effective as each other, and choosing between them depends on which is best for you or best matches your needs. There is no ‘better’ treatment as they both have different benefits depending on the person and their needs.
For example, if you need a longer-lasting treatment, Cialis may be the better treatment for you as it lasts for up to 36 hours. If you need a treatment that’s available over the counter, Viagra Connect might be better for you. What’s important is learning the differences and finding what’s best for you.
There is a large range of ED treatments available at ZAVA. You may find that one treatment works better than another for your ED symptoms.
Can you take Cialis on an empty stomach?
Yes, you can take Cialis with or without food, but what you eat and when you eat can affect how quickly it works. Eating a meal that’s high in fat right before taking your medication can make it take longer to start working.
A few uncommon side effects of Cialis are stomach ache, nausea (feeling sick), or vomiting (being sick). If you get any of these side effects, try eating a small meal before taking Cialis.
Is 20mg of Cialis equal to 100mg of Viagra?
While 20mg is the maximum dose of Cialis and 100mg is the maximum dose of Viagra, they are not directly equal or interchangeable as they are different medications with different active ingredients. Factors such as underlying health conditions and tolerance to the ingredients can affect how your body responds to these medications.
If you are taking the maximum dosage of one of these medications and would like to switch, you should always start with the recommended starting dosage (10mg for Cialis, 50mg for Viagra) to see how your body responds to the new medication, and then increase the dosage if necessary with guidance from your doctor.
Can you take Cialis and Viagra together?
No, you should not take Cialis and Viagra together as it can be unsafe. These medications both work in the same way, so taking both at the same time can increase the risk of side effects such as low blood pressure, dizziness, and priapism (painful long-lasting erections that don’t go away).
Can Cialis lower my blood pressure?
An uncommon side effect of Cialis is low blood pressure. As Cialis works to relax your blood vessels, this could slightly lower your blood pressure temporarily, but this is unlikely to cause any health issues. If you get side effects such as dizziness, blurred vision, heart palpitations, or confusion, this may be a sign of low blood pressure, and you should speak to your doctor straight away if you get these symptoms and stop taking Cialis.
You should not take Cialis if you have been diagnosed with low blood pressure already, as this could cause your blood pressure to drop dangerously low.
Can Cialis cause a heart attack?
A rare side effect of Cialis is a heart attack. Most men who have experienced a heart attack whilst taking Cialis had heart problems before taking the medication. Your doctor will make sure Cialis is a safe and suitable treatment before prescribing it to you.
Always follow your doctor's instructions when taking Cialis, and never take more than your prescribed dose. This could increase the risk of dangerous side effects, especially in men who have heart problems.
What makes Cialis work better?
Things that make Cialis work better include:
- taking it at the right time (around 30 minutes before sex)
- being sexually aroused, you may need to participate in foreplay first
- avoiding alcohol, as this can make it harder to get and maintain an erection
- avoiding heavy, greasy, and fatty meals before taking Cialis, as this can delay its effects
- not putting too much pressure on yourself, as this can make it harder to maintain an erection
If Cialis isn’t working for you after trying it 8 different times, speak to your doctor. You may need a higher dose, or they may suggest trying another ED medication.
While it is beneficial to use medication to treat erectile dysfunction, it is also helpful to find out the cause of your ED. Sometimes ED can occur due to side effects of other medications, such as antidepressants, or due to emotional stress. Psychotherapy can help you to understand if you have any emotional barriers that may be stopping you from getting an erection.
Your doctor will be able to help you find out if any underlying health conditions may be causing your erectile dysfunction.
How often can you take Cialis?
You should not take Cialis more than once a day (24 hours). Cialis can last for up to 36 hours, so you may be able to have sex again the next day without needing another tablet.
Does Cialis work the first time you take it?
Cialis can work the first time you take it, but this isn’t always the case for everyone who tries it. This is because it can take some time for your body to get used to the medication. Due to this, it is recommended to take Cialis on 8 different occasions before trying a different dose or an alternative treatment if it is not working well for you.
What if Cialis doesn’t work for me?
If Cialis doesn’t work for you, try again the next day or the next time you plan to have sex. If you have tried Cialis on more than 8 different occasions and it’s still not working for you, speak to your doctor. They may want to change your dose or recommend a different treatment.
Does Cialis keep you awake?
No, there are no side effects of Cialis that should stop you from sleeping or cause drowsiness.
Can Cialis cause depression?
No evidence shows that Cialis causes depression or low mood. If you think you have depression or a low mood, you should speak to your doctor.
Is Cialis the same as tadalafil?
Yes, Cialis is the branded version of tadalafil, which is the active ingredient in both medications. Both of these medications work in exactly the same way, therefore, Cialis has the same side effects as tadalafil. The only differences between them are the packaging, cost and how the pills look.
Why is Cialis called the ‘weekend pill’?
Cialis is called the weekend pill because its effects can last for most of the weekend (up to 36 hours). This means if you take Cialis on Saturday afternoon, it should last the rest of the weekend.
Brenda studied medicine at St Georges University of London and has most recently worked in John Radcliffe Oxford University Hospitals, covering acute and general medicine.
Meet our doctorsLast reviewed: 14 Aug 2024
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Tadalafil 20 mg film-coated tablets, Patient Information Leaflet [accessed August 2024]
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Tadalafil, National Health Service [accessed August 2024]