Spedra
Spedra tablets help treat erectile dysfunction in adult men.


Prices from £29.00
In stock. Simply fill in a brief questionnaire. One of our doctors will review your order and prescribe a suitable treatment. How to Order
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Spedra contains the active ingredient avanafil and is available in 100mg or 200mg tablets.
Spedra is the brand name of a medication called avanafil. Spedra is manufactured by A.Menarini Farmaceutica Internazionale S.R.L.
Spedra works within 15 to 30 minutes to help you get an erection. This is faster than other erectile dysfunction tablets, like Viagra.
To get Spedra from ZAVA, all you have to do is fill out a quick and simple questionnaire. One of our ZAVA doctors will review your answers and see if Spedra is right for you.
If it is, we can deliver Spedra discreetly to your doorstep.
Prices
4 tablet(s) - £29.00
8 tablet(s) - £49.00
12 tablet(s) - £69.00
16 tablet(s) - £89.00
4 tablet(s) - £37.00
8 tablet(s) - £69.00
12 tablet(s) - £99.00
16 tablet(s) - £129.00



About Spedra
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Spedra is a medication for the treatment of erectile dysfunction (ED). ED is when you find it difficult to get and keep an erection during sex.
The active ingredient in Spedra is avanafil which can help you get and keep an erection. Spedra only works if you’re sexually stimulated so you have to be in the mood for sex for it help you get an erection.
Remember that Spedra will not protect you against sexually transmitted infections (STIs). You can avoid STIs by practising safe sex, including using condoms. If you want more information, talk to a doctor or go to a sexual health clinic for advice.
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To take Spedra:
- swallow one tablet with water 15 to 30 minutes before having sex
- do not take more than one tablet each day
- you can take Spedra with or without food
Avoid drinking alcohol or grapefruit juice whilst taking Spedra, as these can reduce how effective it is.
You will usually be started on a dose of 100 mg. For some people, this dose will be enough to manage their erectile dysfunction. If you find that your starting dose is not effective enough, speak to your doctor and you may be prescribed a higher dose of 200 mg.
If you take too much Spedra, get in touch with your doctor straight away.
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Spedra contains avanafil which blocks a chemical in your body so you can get and keep an erection. This chemical is known as a phosphodiesterase type 5.
ED can be caused by the blood vessels in your penis not allowing enough blood flow in to maintain an erection.
PDE5 inhibitors work by relaxing your blood vessels and allowing more blood flow into your penis. This makes it easier for you to get and keep an erection when having sex.
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Spedra is effective at helping you to get and keep an erection, but only with sexual stimulation. If you eat a high fat meal before taking Spedra, it may be less effective at helping you get an erection.
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Common side effects of Spedra include:
- flushing
- headache
- nasal congestion
Uncommon side effects of Spedra include:
- dizziness
- tiredness
- back pain
- breathlessness
- fast heartbeat
- heart palpitations
- indigestion
- nausea
- vomiting
- sinus congestion
For a full list of the side effects of Spedra, please read the patient information leaflet.
If you experience any side effects when taking Spedra, please get in touch with your doctor as soon as possible.
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You can take Spedra if you’re an adult man with ED.
Do not take Spedra if you:
- are a woman
- are allergic to any of the ingredients
- are taking certain other medications including nitrates and riociguat
- have a serious heart problem
- have had a stroke or heart attack in the past 6 months
- have low blood pressure
- have uncontrolled high blood pressure
- have angina (chest pain)
- have a serious liver or kidney problem
- have non arteritic ischemic optic neuropathy (NAION)
- have a family history of eye problems
Speak to a doctor before taking Spedra if you have or have ever had:
- heart troubles
- priapism
- a condition that affects the shape of your penis
- a bleeding disorder
- peptic ulcers
For more information, you can read the patient information leaflet. If you’re not sure whether you can take Spedra, speak to your doctor or a pharmacist.
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Certain other medications can affect how Spedra works. Tell your doctor about any other medication that you’re taking, or have recently taken, before taking Spedra.
Do not take Spedra if you’re taking or have recently taken:
- nitrate medications, such as amyl nitrite
- some HIV medications such as ritonavir, indinavir, saquinavir, nelfinavir or atazanavir
- antifungal medications such as ketoconazole, itraconazole or voriconazole
- certain antibiotics such as clarithromycin or telithromycin
- other medications for erectile dysfunction (ED)
Speak to your doctor before taking Spedra if you’re taking or have recently taken:
- alpha blockers
- antibiotics such as erythromycin
- epilepsy medications such as phenobarbital, primidone or carbamazepine
- medications for arrhythmia such as quinidine, procainamide, amiodarone or sotalol
- riociguat
For more information, please read the patient information leaflet.
If possible, you should try and avoid drinking large amounts of alcohol when taking Spedra. Alcohol can interfere with Spedra and make it less effective. Alcohol can also make it more difficult to maintain an erection, contributing to ED.
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If you do not think Spedra is right for you, there are alternative erectile dysfunction treatments including:
Some ED medications may be more effective for some people than for others.
Speak to your doctor if you’d like to try an alternative treatment and they can give you advice on the right one for you.

Babak studied medicine at King’s College London and graduated in 2003, having also gained a bachelor’s degree in Physiology during his time there. He completed his general practice (GP) training in East London, where he worked for a number of years as a partner at a large inner-city GP practice. He completed the Royal College of GPs membership exam in 2007.
Meet our doctorsLast reviewed: 17 Feb 2022
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Spedra 100mg patient information leaflet [April 2018] [accessed Dec 2021]

GMC: 6149061

GMC: 7074021

GMC: 7155722


ZAVA offers a convenient and discreet service to help men improve their erectile dysfunction. There are a number of treatments you can consider. Continue to our erectile dysfunction service page to learn about the treatment options available.
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