Order Melatonin Tablets
Circadin is a medication used to treat jet lag. It contains a hormone called melatonin, which regulates the sleep-wake cycle, or “body-clock”.
Order melatonin tablets from Zava and enjoy your holidays without suffering from jet lag. To place an order, you need to fill in a short medical questionnaire and select your preferred treatment. Our online doctor will review your answers and approve appropriate treatment. Once approved, your medication is dispatched without delay. Orders placed before 4pm will be processed the same day.
Melatonin is currently not licensed for use in jet lag in the UK. However, if you're medically suitable, we can still prescribe it for jet lag, as long as you're aware of this. Melatonin is licensed for use to treat insomnia, but a large scientific review has approved its use for prevention of jet lag.
10 tablet(s) / 2 mg - £24.99
20 tablet(s) / 2 mg - £34.99
Circadin contains the active ingredient melatonin, a hormone which naturally occurs in the human body. Depending on the time of the day, your blood levels of melatonin vary. The hormone forms part of your “body clock” and determines at which time you feel awake and and which time you feel tired. Your body increases the production of melatonin when it gets dark, which is why you begin to feel increasingly sleepy as the evening progresses.
When you take a long-distance flight, you cross time zones. As a result, the cycle of day and night that you are used to is interrupted. It will get dark at a different time at your destination, which can be difficult to adjust to. Your body needs to get used to the new time zone and produce melatonin at a different time to allow you to sleep at night. In order to help your body get used to the new routine, you can take Circadin. You need to take a melatonin tablet in the evening before you want to sleep. The melatonin in the tablets will help you sleep when it is night at your travel destination. This way, your body clock will get used to the new time zone quickly.
Melatonin is currently not licensed for use in jet lag in the UK. It is licensed for use to treat insomnia, but a large scientific review has approved its use for prevention of jet lag.
You need to take one Circadin tablet 1 - 2 hours before you go to bed. Take the tablet after a meal with a glass of water. Swallow the tablet whole without crushing or chewing it. When you order Circadin prolonged-release tablets from Zava, you will receive a packet of 10 tablets. You should take one on the first night in your new destination, just before bedtime. You can also take a tablet in the same way for the next 2-3 days if needed, until you feel that you have adjusted to the new time zone. (You may also want to repeat this process after your flight home again).
Do not take more than one tablet per day. If you have forgotten one dose, continue your treatment with one tablet the following evening - do not double the dose to make up for the one you have missed.
Each Circadin tablet contains 2mg of the active ingredient melatonin. You can stop taking your melatonin tablets whenever you feel you have adjusted to the new time zone. The medication does not cause any withdrawal symptoms or problems with sleeping.
In addition to 2mg melatonin, Circadin contains ammonio methacrylate copolymer type B, calcium hydrogen phosphate, dihydrate, lactose monohydrate, silica (colloidal anhydrous), talc and magnesium stearate.
Circadin causes side effects in some patients. Seek medical help immediately if you encounter the following side effects:
- chest pain
- visual disturbances
- dizziness or a spinning sensation
- feeling disoriented
- blood cells in your urine
- increased bleeding or bruising
- changes in your blood levels of certain cells (may show in blood tests)
- psoriasis (a skin rash)
Most people tolerate Circadin well. However, the following side effects have been observed:
- changes in mood such as irritability, restlessness and nervousness
- headaches and migraine
- insomnia, unusual dreams and nightmares
- abdominal pain and indigestion
- lethargy and tiredness
- high blood pressure
- pain in the extremities
- mouth ulcers
- feeling weak
- changes in the composition of your blood (will show in blood tests)
- jaundice (yellowing of skin and eyes)
- inflammation of the skin, dry skin, itchy skin or skin rash
- sweating at night
- weight gain
- changes in your liver function
- excretion of glucose in the urine
- menopausal symptoms
- excess excretion of proteins in the urine
Do not drive or operate machinery if Circadin is making you feel drowsy.
For all known side effects of Circadin, read the patient leaflet supplied with your melatonin tablets.
Melatonin tablets can interact with certain other medications, such as:
- other sleeping tablets and sedatives
- beta-blockers and some other blood pressure medications
- NSAIDs e.g. ibuprofen
- oestrogens (for example the contraceptive pill and medications used for hormone replacement therapy)
- fluvoxamine (used to treat psychiatric conditions)
- psoralens (used to treat certain skin conditions)
- imipramine (for the treatment of depression)
- the epilepsy medication carbamazepine
- thioridazine (used to treat schizophrenia)
- certain anti-depressants
- adrenergic agonists/antagonists (used to treat a range of conditions, including high blood pressure and nasal congestion)
- opiate agonists/antagonists (used to treat drug addiction)
- prostaglandin inhibitors (including non-steroidal anti-inflammatories)
- Benzodiazepines and non-benzodiazepine hypnotics
Do not take melatonin tablets if you are allergic to melatonin or any other ingredient in the tablets.
Alcohol and tobacco can reduce the effectiveness of melatonin tablets. Abstain from smoking tobacco and drinking alcohol while taking Circadin.
- liver or kidney problems
- an intolerance to certain sugars
- an autoimmune disease