Melatonin

1. Take one to two 3mg tablets on the first night in your new destination.
2. Continue to take one or two tablets per night if you think you’ll have trouble sleeping, for a maximum of 5 nights.

You’ll need to take 1 tablet, up to 2 hours before you want to go to bed. You should not consume food for 2 hours before or after taking the medication. You should swallow the tablet whole, and not crush or chew it. You should also avoid drinking alcohol when taking melatonin, because that can make it less effective.

You shouldn’t feel any withdrawal symptoms or issues sleeping after you stop using melatonin tablets.

You can order melatonin from ZAVA and this service is quick and easy to use.

Simply:

1. fill out a short online assessment about your health and lifestyle
2. place an order for your preferred treatment option
3. a doctor wil assess your treatment to see if your order is right for you

If approved, we’ll post your order to your preferred address in discreet packaging.

Melatonin is normally well tolerated, which means it usually doesn’t cause side effects.

Uncommon side effects

Uncommon side effects of melatonin can include:

• mood changes like restlessness, nervousness, and irritability
• headaches
• migraine
• insomnia
• dizziness
• feeling weak
• tiredness
• high blood pressure
• mouth ulcers
• abdominal pain
• night sweats
• pain in the extremities
• abnormal liver function
• weight gain
• skin problems
• abdominal pain and indigestion
• changes in blood composition

If you get any of the following side effects while taking melatonin, you should get medical attention as soon as possible:

• chest pain
• palpitations (an irregular heart beat)
• depression
• visual disturbances
• feeling disorientated
• increased bleeding or bruising
• psoriasis

Active ingredient:

• melatonin

Other ingredients:

• ammonio methacrylate copolymer type B
• calcium hydrogen phosphate dihydrate
• lactose monohydrate
• silica (colloidal anhydrous)
• talc

ZAVA offers 3mg doses

Each film-coated tablet contains 3mg of melatonin. The standard dose is 3mg (1 tablet) daily for a maximum of 5 days. The first dose should be taken upon arrival at your destination at the habitual bed-time.

Due to the potential for incorrectly timed intake of melatonin to have no effect, or an adverse effect, on re-synchronisation following jet-lag, Melatonin 3mg film-coated tablets should not be taken before 8pm or after 4am at destination.

Food can enhance the increase in plasma melatonin concentration. Intake of melatonin with carbohydrate-rich meals may impair blood glucose control for several hours. It is recommended that food is not consumed 2 hours before and 2 hours after intake of Melatonin 3mg film-coated tablets.

As alcohol can impair sleep and potentially worsen certain symptoms of jet lag (e.g. headache, morning fatigue, and concentration) it is recommended that alcohol is not consumed when taking Melatonin 3mg film-coated tablets.

Melatonin 3mg film-coated tablets may be taken for a maximum of 16 treatment periods per year.

Melatonin must not be used with any other sedative medications or sleeping tablets.

Melatonin can interact with other medications - please check with your doctor if you are taking any other medicines (prescription or over the counter).

Possible side effects of the medication

WARNING: Melatonin will cause drowsiness therefore should only be used at bedtime and not when drowsiness could pose a danger to your safety and well-being (e.g. if driving or using machinery).

Drowsiness/sleepiness, headache, and dizziness/disorientation are the most frequently reported adverse effects when melatonin is taken on a short-term basis to treat jet lag. Drowsiness, headache, dizziness, and nausea are also the adverse effects reported most frequently when typical clinical doses of melatonin have been taken for periods of several days to several weeks by healthy persons and patients. For a full list of side effects, please refer to the patient information leaflet.